Defective Secretion of an Immtmoglobulln Caused by ... - Europe PMC
Defective Secretion of an Immtmoglobulln Caused by Mutations in the Heavy Chain Complementarity Determining Region 2 By Ching Chen, TammyM. Martin, SusanStevens, and Marvin B. Kittenberg From the Department of Microbiology and Immunology, Oregon Health Sciences University, Portland, Oregon 97201
Summary We have investigated four secretion-deficient antibodies (Abs) derived from a panel of 46 mutant T15 anti-phosphocholine Abs, all of which have point mutations in the heavy chain (H) complementarity determining region 2 (CDK2). The level of secretion for these four Abs was
Summary We have investigated four secretion-deficient antibodies (Abs) derived from a panel of 46 mutant T15 anti-phosphocholine Abs, all of which have point mutations in the heavy chain (H) complementarity determining region 2 (CDK2). The level of secretion for these four Abs was
