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Key Summary

Increased Hepatitis C Virus (HCV) Detection in Women of Childbearing Age and Potential Risk for Vertical Transmission - United States and Kentucky, 2011-2014

Article Publication Background    

Between 2010 and 2014, the incidence of hepatitis C virus (HCV) infection 1 increased among women ≤30 years of age in the United States. The increased incidence raises concerns about the number of infants exposed to HCV at birth because HCV is transmitted to ~6% of infants born 2 to HCV-infected women (vertical transmission). Trends in HCV testing and test results may inform screening recommendations for pregnant women. Objective: Investigators evaluated the potential for mother-to-child transmission by examining rates of 1) HCV infection among women of childbearing age (WCBA), 2) HCV testing among infants, and 3) infants born to HCV-infected mothers.

Article published in the Morbidity and Mortality Weekly Report Authors

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Alaya Koneru, Noele Nelson, Susan 1 1 Hariri, Lauren Canary, Kathy J 2 2 Sanders, Justine F Maxwell, Xiaohua 3 3 Huang, John AD Leake, John W 1 1 Ward, Claudia Vellozzi

Affiliation 1

Methods  

This study included testing data collected at the laboratory of Quest Diagnostics from 2011 through 2014. Infection rates among WCBA and testing rates among infants born to HCVinfected mothers were determined for the United States and Kentucky, the 1 state with the highest rate of acute HCV infection between 2011 and 2014. o HCV antibody and RNA testing data were used to determine infection rates in WCBA and testing rates in infants. o Birth certificate data were used to determine the rate of infants (