Background Methods Conclusion Results
Factors that Influence the Willingness of Young Adults to Participate in Early Vaccine Trials and Contraceptive Practices in Dar es Salaam, Tanzania 1
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2a 3 2b 4 Edith Tarimo , Eric Sandstrom , Muhammad Bakari and Asli Kulane
Theodora Mbunda , Guerino Chalamilla 1 2a 2b Infectious Disease Clinic,MDH Department of Nursing and Internal Medicine, Muhimbili University of Health and Allied Sciences (MUHAS), Dar es Salaam, Tanzania. 3 4 Venhalsan, Karolinska Institutet, Sodersjukhuset, Stockholm, Sweden. Department of Public Health Sciences, Global Health, Karolinska Institutet., Stockholm, Sweden.
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Background HIV/AIDS destroys the lives of young people especially in low-income countries. The inclusion of youths in HIV vaccine trials is necessary in obtaining an effective vaccine that is acceptable to them. Participation in HIV vaccine trials however necessitates participants not to become pregnant or impregnate women. Therefore it is important to study factors influencing willingness to participate and dynamics of contraceptive practices among young adults." "
Methods Four hundred and fifty young adults visited a youth-friendly Infectious Diseases Clinic (IDC) from February to September 2012 completed a self-administered questionnaire concerning sociodemographic information, contraceptive practices, knowledge and perception of HIV vaccine studies, and the availability of social support."
Acknowledgements! All youth volunteers, staff at IDC, collaborators at Karolinska Institute MDH and MUHAS.Support by Sida through Tanzania and Swedish collaboration .
Results Of our participants, 50.6% expressed willingness to participate. The willingness was positively correlated with having some knowledge about HIV vaccine studies (AOR, 2.2; 95% CI: 1.4-3.4), a positive perception toward such studies (AOR, 2.3; 95% CI: 1.5-3.6) having a relationship with someone who could help them make a decision (AOR, 2.5; 95% CI: 1.3-4.9), and age at the time of sexual debut (AOR, 2.6; 95% CI 1.0-6.7) for 15- to 19-year-olds and (AOR, 2.7; 95% CI 1.0-7.1) for older participants. 73% of those expressing WTP knew contraception was for spacing children, 45% and 49% reported to ever use contraceptives and to use them at time of last sexual intercourse. The reasons for not using contraceptives were not being married; lack of knowledge on contraceptives; and having unplanned sexual intercourse "
Conclusion The participants exhibited a moderate willingness to participate in HIV vaccine trials, less than half reported to use contraceptives. More efforts should be made to inform the youths about specific HIV vaccine trials, to engage significant others in the decision-making process, and to address impediments pertaining to contraceptive use in the Tanzanian context."
1,
"
2a 3 2b 4 Edith Tarimo , Eric Sandstrom , Muhammad Bakari and Asli Kulane
Theodora Mbunda , Guerino Chalamilla 1 2a 2b Infectious Disease Clinic,MDH Department of Nursing and Internal Medicine, Muhimbili University of Health and Allied Sciences (MUHAS), Dar es Salaam, Tanzania. 3 4 Venhalsan, Karolinska Institutet, Sodersjukhuset, Stockholm, Sweden. Department of Public Health Sciences, Global Health, Karolinska Institutet., Stockholm, Sweden.
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Background HIV/AIDS destroys the lives of young people especially in low-income countries. The inclusion of youths in HIV vaccine trials is necessary in obtaining an effective vaccine that is acceptable to them. Participation in HIV vaccine trials however necessitates participants not to become pregnant or impregnate women. Therefore it is important to study factors influencing willingness to participate and dynamics of contraceptive practices among young adults." "
Methods Four hundred and fifty young adults visited a youth-friendly Infectious Diseases Clinic (IDC) from February to September 2012 completed a self-administered questionnaire concerning sociodemographic information, contraceptive practices, knowledge and perception of HIV vaccine studies, and the availability of social support."
Acknowledgements! All youth volunteers, staff at IDC, collaborators at Karolinska Institute MDH and MUHAS.Support by Sida through Tanzania and Swedish collaboration .
Results Of our participants, 50.6% expressed willingness to participate. The willingness was positively correlated with having some knowledge about HIV vaccine studies (AOR, 2.2; 95% CI: 1.4-3.4), a positive perception toward such studies (AOR, 2.3; 95% CI: 1.5-3.6) having a relationship with someone who could help them make a decision (AOR, 2.5; 95% CI: 1.3-4.9), and age at the time of sexual debut (AOR, 2.6; 95% CI 1.0-6.7) for 15- to 19-year-olds and (AOR, 2.7; 95% CI 1.0-7.1) for older participants. 73% of those expressing WTP knew contraception was for spacing children, 45% and 49% reported to ever use contraceptives and to use them at time of last sexual intercourse. The reasons for not using contraceptives were not being married; lack of knowledge on contraceptives; and having unplanned sexual intercourse "
Conclusion The participants exhibited a moderate willingness to participate in HIV vaccine trials, less than half reported to use contraceptives. More efforts should be made to inform the youths about specific HIV vaccine trials, to engage significant others in the decision-making process, and to address impediments pertaining to contraceptive use in the Tanzanian context."
