Biochemistry Exam II Electron Transport Chain

ELECTRON TRANSPORT CHAIN

GLYCOLYSIS

MALATE-ASPARTATE SHUTTLE NAD

GLYCOLYSIS

NADH + H+

NAD

NADH + H+

GLYCEROL-P SHUTTLE

Malate

Glycerol-3-P

Oxaloacetate

α-KG

Asp

Dihydroxyacetone phosphate

Glu

CYTOSOL INTER-MEMBRANE SPACE NADH-Q Reductase Inhibited by: Roteone Amytal 4H+

QH2-Cytochrome C Reductase Inhibited by: Antimycin A 1e- shuttle 4H+

I

2e- shuttle

Fe-S

FAD

FMN 2e-

2e-

II

Glu

NADH + H+

NAD

Succinate Malate

Succinate DH

Asp

Cyt C

ATP Synthase F0 Inhibited by: nH+ Oligomycin

F0

IV

Q

FADH2

F1 2e-

2e-

α-KG

III

Cytochrome C Oxidase Inhibited by: HCN, CO H2S, N3- (azide) 2H+

Yo Mama

1/2 O2 + 4H+

H2O

ADP

ATP

Fumarate

Oxaloacetate Acyl-CoA DH

CITRIC ACID CYCLE FA-CoA NAD

NADH + H+

FA β-OXIDATION

MITOCHONDRIAL MATRIX