Lecture: FERMENTATION Outline: 1. Review of Glycolysis o 2 fates of pyruvate
2. Fermentation o Alcohol fermentation o Lactic acid fermentation
Glycolysis Review o The step-by-step breakdown (oxidation) of glucose to ____________ 1 glucose
1. Review of glycolysis o
2. Fermentation o
Alcohol fermentation
o
Lactic acid fermentation
ATP
ATP
Investment phase Fructose-1-6-bisphosphate
G3P
NAD+
DHAP
G3P
NAD+
NADH
NADH
ADP
ADP
ATP
ATP
Payoff phase
Pyruvate
ADP
ADP
ATP
ATP Pyruvate
Total energy so far: +2 ATP, 2 NADH
2 fates of pyruvate
Glycolysis Review
1. Review of glycolysis
o Pyruvate has 2 possible fates: ➢ Citric acid cycle: when oxygen is present
(_______________) ➢ Fermentation: when oxygen is absent (_______________) Pyruvate O2 Citric acid cycle
No O2 Fermentation
Total energy so far: +2 ATP, 2 NADH
o
2 fates of pyruvate
2. Fermentation o
Alcohol fermentation
o
Lactic acid fermentation
Fermentation Occurs in the absence of oxygen o Purpose: to oxidize NADH back to NAD+ so that it can be recycled in another round of glycolysis o Two types: ➢ Ethanol fermentation: prokaryotes and
yeast. Product is ________________. ➢ Lactic acid fermentation: mammals. Product is ______________. Pyruvate
Pyruvate
CO2 NADH NAD+ NADH NAD+
Ethanol
Lactate
Total energy so far: +2 ATP, ATP 2 NADH
1. Review of glycolysis o
2 fates of pyruvate
2. Fermentation o
Ethanol fermentation
o
Lactic acid fermentation
Fermentation NAD+ is recycled o NAD+ is required to _________________________