Sup Fig. 2 APP/ DAPI

A

MEDGC (Scrambled)

GSAP Oligo 2

GSAP Oligo 1

GSAP Oligo 3

GSAP Oligo 4

APP/ DAPI

APP (6E10) Fluorescence intensity normalized to cell number

B 1.2 1 0.8 0.6

**

**

**

**

GSAP oligo 1

GSAP oligo 2

GSAP oligo 3

GSAP oligo 4

0.4 0.2 0 MEDGC

siRNA

Sup Fig. 2