VARSS 2016 highlights

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UK-VARSS

2016

Highlights Report

Antibiotic Sales and Usage Overall trends in mg/kg The Government committed to reduce antibiotic use in livestock and fish farmed for food to a multi-species average of 50 mg/kg by 2018, from 62 mg/kg in 2014. This has been achieved two years early, with antibiotic use in food-producing animal species decreasing by 27% to 45 mg/kg.

= 50 mg/kg target 70

62

57

45

2015

2016

Total in mg/kg

60 50 40 30 20 10 0

2014

Sales of highest priority critically important antibiotics (HP-CIAs) have also reduced in 2016 from an already low level. Sales of 3rd/4th generation cephalosporins reduced by 12% to 0.15 mg/kg, fluoroquinolones reduced by 29% to 0.24 mg/kg, and colistin reduced by 83% to 0.02 mg/kg, which is considerably below the 1 mg/kg maximum target for colistin recommended by the European Medicines Agency.

Compared with 2015

2012

2013

2014

2015

2016

66

62

62

57

45

21%

Fluoroquinolones (FQ) (mg/kg)

0.33

0.36

0.35

0.34

0.24

29%

3rd/4th gen Cephalosporins (mg/kg)

0.20

0.18

0.19

0.17

0.15

12%

Colistin (mg/kg)

0.09

0.11

0.12

0.12

0.02

83%

Total sales (tonnes)

464

436

445

408

337

17%

Total (mg/kg)

Total sales in tonnes of active ingredient by class for 2016

= 1 tonne

Tetracyclines, β-lactams and trimethoprim/sulphonamides accounted for the majority (78%) of active antibiotic ingredient sold. As with previous years, HP-CIAs (fluoroquinolones, colistin and 3rd/4th generation cephalosporins) accounted for a small proportion of the sales (