15FNA4 Mediatstinal 57b9469b ae6f 9720 14a2 13b8118775eb

FNA Cytopathology 15FNA4 Specimen: FNA mediastinal mass Clinical Notes: Male, 22 years. Presents with chest pain. CT scan shows a 12 mm anterior mediastinal mass without calcification and with homogenous attenuation. Expected Response: Seminoma.

Figure 1. Highly cellular dyscohesive smear showing malignant bare nuclei, stripped cytoplasm (Pap).

Figure 2. Smears show a population of smaller lymphoid cells and macrophages (DQ).

Figure 3. Round-ovoid malignant bare nuclei in a background of lymphocytes, plasma cells, eosinophils and macrophages (DQ).

Figure 4. Round-ovoid malignant bare nuclei background lymphocytes, and macrophages. Note prominent nucleoli (Pap).

Figure 5. Fragile cells result in trails of nuclear debris and

Figure 6. Malignant nuclei with trails of nuclear debris across the field. Note the characteristic ‘tigroid background’ (DQ).

dispersed cytoplasmic fragments in the smear background (Pap).