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Cracking the Code:

The Economic Impact of San Diego’s Genomics Industry BIO International June 19, 2017

“The ultimate promise of the genome is for health preservation. There’s a beautiful story around genomics that’s about personal wellness and societal health.” - Dawn Barry, Vice President, Applied Genomics, Illumina

Defining the Industry Local universities, research institutes and commercial entities that work collaboratively to unlock the power of the human genome.

Health IT

Tech companies that provide data storage and software solutions, enabling practitioners to deliver datadriven personalized medicine.

Biotechnology R&D

Genomics

Biomedical Device MFG

Companies that research, develop and manufacture new drugs and therapies for personalized medicine.

Pharmaceuticals

Companies with sequencing technologies that produce NextGeneration Sequencing (NGS) devices.

Economic Impact

115+ FIRMS

$5.6B

ECONOMIC IMPACT

10,055 DIRECT JOBS

Economic Impacts Impact Type

Employment

Valued Added

Wages

($Millions)

($Millions)

Direct

10,055 $

2,954.6 $

1,577.0

Indirect

12,720 $

1,532.3 $

1,033.3

Induced

12,240 $

1,084.9 $

606.7

Tot al Im pact

35,015 $

5,571.8 $

3,217.0

Mult iplier

3.5

1.9

2.0

Direct Employment by Industry

50%

18%

Scientific R&D

Biopharmaceutical MFG

Diagnostic Laboratories

Software & IT Services

14%

12%

Med Devices & Supplies

7%

Economic Impacts $373M Annually

State & Local Tax Impact ($Millions)

$7.8

Employee/Employer Social Contribution

$26.9

Corporate Profits

$116.3

Personal Income, Property and Licensing

$222.0

Corporate Sales, Property and Licensing

0

50

100

150

200

250

Genomics Scorecard

Concept & Methodology • Score the top 10 life science markets on the relative strength of their genomics ecosystem

• “Scorecard” approach to simplify complicated measures. • Three main categories (9 measures total) • Simple / classic standardization and curving techniques (50-100 range) • Think typical school / classroom grading

Limitations • Genomics is not a typical classification in data sources, so we must come up with more creative measures

• Data must be comparable and consistent across geographic units • Data must be presented in a way that people can understand • Data should represent strength of the market

Comparison Markets MSA

Principal City

Boston-Cambridge-Newton, MA-NH

Boston

Chicago-Naperville-Elgin, IL-IN-WI

Chicago

Indianapolis-Carmel-Anderson, IN

Indianapolis

Minneapolis-St. Paul-Bloomington, MN-WI

Minneapolis

Philadelphia-Camden-Wilmington, PA-NJ-DE-MD

Philadelphia

Raleigh, NC

Raleigh

Salt Lake City, UT

Salt Lake City

San Diego-Carlsbad, CA

San Diego

San Francisco-Oakland-Hayward, CA

San Francisco

San Jose-Sunnyvale-Santa Clara, CA

San Jose

Criteria: 1. SIZE: Metro population must be greater than 1M 2. CONCENTRATION: Top 10 most concentrated markets based on life science employment

Comparative Data Talent • TALENT PIPELINE Degree Completions in GenomicsRelated Fields (per 10k workers)

• TALENT POOL Number of People Employed in Key Occupations (LQ)

Innovation • FEDERAL FUNDING Avg. Annual Federal Funding for Genomics 2014-2016 (per $mil GDP)

• VENTURE CAPITAL Avg. Annual VC Dollars Received by Genomics Companies 2014-2016 (per $mil GDP)

Growth • JOB POSTINGS Unique Genomics Job Postings in 2016 (per 10k workers)

• PROJECTED GROWTH Projected Genomics Occupation Growth 2016-2021 (%)

• TALENT SPECIALIZATION Concentration of Key Occupations in Genomics Industry

• PATENTS Patents in Genomic Technologies (per 100k workers)

• HISTORIC GROWTH Historic Genomics Occupation Growth 2011-2016 (%)

Overall Rankings

Genomics Scorecard

BOTTOM

MIDDLE

TOP

Overall Rank

MSA

Talent

Innovation

Growth

Overall Score

Score

Rank

Score

Rank

Score

Rank

1

Boston

91.3

98.2

1

92.1

1

83.7

5

2

San Diego

90.2

95.0

2

90.4

2

85.4

4

3

San Francisco

87.7

89.5

3

83.0

4

90.7

2

4

San Jose

82.3

75.9

7

83.6

3

87.3

3

5

Salt Lake City

77.0

74.4

8

64.4

7

92.3

1

6

Philadelphia

76.0

86.8

4

71.9

5

69.4

10

7

Raleigh

75.4

81.7

5

62.4

10

82.3

6

8

Indianapolis

73.5

79.9

6

62.4

9

78.2

7

9

Minneapolis

72.1

73.7

9

69.3

6

73.2

8

10

Chicago

68.7

73.4

10

62.4

8

70.3

9

Innovation Capital fuels growth in genomics. San Diego’s exceptional track record for generating lucrative intellectual property and developing strong life sciences companies allows us to command a large share of genomics-related VC.

$38M

371

$292M

Federal Funding

Patents in Genomics

VC Dollars Received

2016

2014 - 2016

2016

Specialized Talent The genomics industry benefits from the talent being supplied by the region’s top academic institutions. Quality of life and abundant job opportunities are two primary reasons San Diego has a higher-than-average concentration of genomics talent; a fundamental ingredient for a healthy ecosystem.

6,957

3.1X

1,956

Employed in Key Genomics Occupations

Concentration in Key Genomics Occupations

Genomics-Related Degrees Conferred

2016

2016

2015

Growth Companies are born out of our research institutions. Technological advancements drive demand for talent. San Diego’s strong growth over the past five years is projected to continue into the future.

11%

2,939

10%

Industry Growth

Unique Job Postings

Projected Growth

2011-2016

2016

2016 - 2021

San Diego is… Collaboration & Leadership

End-to-End Genomics

An Attractive Market for Investment

A Platform for Precision Medicine

“It’s much more than genomics; San Diego is the ultimate place for research, sequencing technologies and the demonstration of human longevity, giving us a natural platform for precision medicine. Ultimately it’s about better personalized health and that’s what the vision for our region is.” - Mark Stevenson, Executive Vice President and President, Life Sciences Solutions, Thermo Fisher Scientific

UNDERWRITTEN BY

RESEARCH SUPPORT BY

SPONSORED BY

Kirby Brady Research Director, San Diego Regional EDC [email protected]