Family history

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Ten Minutes Familial Risk Counseling Boosts and Maintains the Effect of Lifestyle Intervention for the Prevention of Diabetes Masakazu Nishigaki, PhD, RN, CGC

Yuri Tokunaga-Nakawatase, PhD, RN

Junko Nishida, MD

Keiko Kazuma

Kyoto University, Kyoto, Japan

Yokohama City University, Yokohama, Japan

Tokyo Yamate Medical Center, Tokyo, Japan

The University of Tokyo (former), Tokyo, Japan

Key points ・Family history is a strong risk factor of type 2 diabetes. ・Six-page booklet enabled brief diabetes genetic counseling. ・Diabetes genetic counseling boost and maintain the effect of lifestyle intervention on energy intake.

Background Several diabetes prevention trials using genotyping and genetic counseling showed that such strategies are not meant to replace traditional risk counseling. Family history (FH), reflecting both genetic and lifestyle characteristics, is still an effective public health tool to identify high risk individual in this post genomic era.

Participants and setting

Results

Participants

Energy Intake

Healthy adults (30- 60 years) with family history of type 2 diabetes in the first degree relatives. Setting: A health check-up center in Tokyo.

lifestyle intervention Genetic Counseling

Intervention 10-minutes Diabetes Genetic Counseling n=69, 63

Six-page booklet for Diabetes Genetic Counseling Developed based on Health Belief Model Severity What is diabetes?

Objective

n=47, 47

n=53, 52

Physical Activity

Susceptibility & Controllability Benefits & Barriers

Susceptibility for diabetes

the effect of diabetes genetic counseling for healthy adults with diabetes family history

Fat/Energy ratio

Susceptibility

Increasing diabetes

To investigate

n=64, 59

Susceptibility and family history

Genetic Counseling

lifestyle intervention

Genetic Counseling

lifestyle intervention

Those who have FH will surely get diabetes ?? Lifestyle modification for Diabetes prevention

Methods

Conclusion

Design: unmasked, two-arm randomized control trial (trial registry no. UMIN000003589) Intervention Group

Control Group

Diet

Familial risk Exercise

Genetic Counseling AND 6-month Life style intervention

Diet

vs.

Exercise

6-month Life style intervention only

Nishigaki et al. Adv Prevent Med 2011;ID_365132

Outcomes Changes in lifestyle energy intake, fat/energy ratio, physical activity

10-minutes diabetes genetic counseling succeed to: boost and maintain the effect of lifestyle intervention on energy intake failed to: change fat/energy ratio and physical activity Intervention development: Nishigaki et al. Adv Prevent Med 2011;ID_365132 Study protocol: Nishigaki et al. J Nutr Metab. 2012; 831735 Secondary outcomes: Nishigaki et al. J Genet Couns 2014; 23(5): 762-9.