Ten Minutes Familial Risk Counseling Boosts and Maintains the Effect of Lifestyle Intervention for the Prevention of Diabetes Masakazu Nishigaki, PhD, RN, CGC
Yuri Tokunaga-Nakawatase, PhD, RN
Junko Nishida, MD
Keiko Kazuma
Kyoto University, Kyoto, Japan
Yokohama City University, Yokohama, Japan
Tokyo Yamate Medical Center, Tokyo, Japan
The University of Tokyo (former), Tokyo, Japan
Key points ・Family history is a strong risk factor of type 2 diabetes. ・Six-page booklet enabled brief diabetes genetic counseling. ・Diabetes genetic counseling boost and maintain the effect of lifestyle intervention on energy intake.
Background Several diabetes prevention trials using genotyping and genetic counseling showed that such strategies are not meant to replace traditional risk counseling. Family history (FH), reflecting both genetic and lifestyle characteristics, is still an effective public health tool to identify high risk individual in this post genomic era.
Participants and setting
Results
Participants
Energy Intake
Healthy adults (30- 60 years) with family history of type 2 diabetes in the first degree relatives. Setting: A health check-up center in Tokyo.
the effect of diabetes genetic counseling for healthy adults with diabetes family history
Fat/Energy ratio
Susceptibility
Increasing diabetes
To investigate
n=64, 59
Susceptibility and family history
Genetic Counseling
lifestyle intervention
Genetic Counseling
lifestyle intervention
Those who have FH will surely get diabetes ?? Lifestyle modification for Diabetes prevention
Methods
Conclusion
Design: unmasked, two-arm randomized control trial (trial registry no. UMIN000003589) Intervention Group
Control Group
Diet
Familial risk Exercise
Genetic Counseling AND 6-month Life style intervention
Diet
vs.
Exercise
6-month Life style intervention only
Nishigaki et al. Adv Prevent Med 2011;ID_365132
Outcomes Changes in lifestyle energy intake, fat/energy ratio, physical activity
10-minutes diabetes genetic counseling succeed to: boost and maintain the effect of lifestyle intervention on energy intake failed to: change fat/energy ratio and physical activity Intervention development: Nishigaki et al. Adv Prevent Med 2011;ID_365132 Study protocol: Nishigaki et al. J Nutr Metab. 2012; 831735 Secondary outcomes: Nishigaki et al. J Genet Couns 2014; 23(5): 762-9.