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PARTICIPATING FACULTY Economic Impact of Irritable Bowel Syndrome: What Does the Future Hold? This supplement to The American Journal of Managed Care contains information regarding the economic and medical impact of irritable bowel syndrome. This supplement has been reviewed by an expert in the field.

Faculty Daniel Aguilar, MPH Research Associate Cerner Health Insights Los Angeles, California

Joaquim Fernandes, BA Senior Analyst Aetna Health Information Solutions Blue Bell, Pennsylvania

Hannah Kurth, BA Manager Innovative Health Solutions Brookline, Massachusetts

Victoria Barghout, MSPH Associate Director Health Economics and Outcomes Research Novartis Pharmaceuticals Corporation East Hanover, New Jersey

Feride Frech, MPH Director, Outcomes Research Health Economics and Outcomes Research Novartis Pharmaceuticals Corporation East Hanover, New Jersey

Joshua J. Ofman, MD Vice President Reimbursement and Payment Policy Amgen Incorporated Thousand Oaks, California

Jane F. Beaulieu, MSN Senior Clinical Analyst Aetna Health Information Solutions Blue Bell, Pennsylvania

Ian M. Gralnek, MD, MSHS Assistant Professor of Medicine David Geffen School of Medicine University of California Los Angeles VA Greater Los Angeles Healthcare System CURE Digestive Diseases Research Center Center for the Study of Digestive Healthcare Quality and Outcomes Los Angeles, California

Judith Bentkover, PhD President and CEO Innovative Health Solutions Brookline, Massachusetts Michael A. Bloom, BA Senior Consultant Innovative Health Solutions Brookline, Massachusetts Stephen J. Boccuzzi, PhD Chief Information Officer Aetna Health Information Solutions Blue Bell, Pennsylvania Brooks Cash, MD, FACP Assistant Professor of Medicine Uniformed Services University of the Health Sciences Bethesda, Maryland Bonnie B. Dean, PhD Associate Director Cerner Health Insights Los Angeles, California

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David Groves, PhD Vice President Corporate Health Management Comerica Incorporated Detroit, Michigan Samuel Joo, MS Senior Analyst Aetna Health Information Solutions Blue Bell, Pennsylvania Kristijan H. Kahler, SM Director Health Economics and Outcomes Research Novartis Pharmaceuticals Corporation East Hanover, New Jersey

Dean G. Smith, PhD Professor and Chair Department of Health Management and Policy University of Michigan School of Public Health Ann Arbor, Michigan Brennan M. R. Spiegel, MD, MSHS Assistant Professor of Medicine Department of Gastroenterology and Hepatology VA Greater Los Angeles Healthcare System David Geffen School of Medicine University of California Los Angeles Center for the Study of Digestive Healthcare Quality and Outcomes Los Angeles, California Judith J. Stephenson, SM Senior Research Associate Aetna Health Information Solutions Blue Bell, Pennsylvania Sean Sullivan, JD President and Chief Executive Officer Institute for Health and Productivity Management Scottsdale, Arizona

THE AMERICAN JOURNAL OF MANAGED CARE

APRIL 2005

Faculty Disclosure It is the policy of The American Journal of Managed Care to have all faculty who participate in programs sponsored by corporate organizations disclose any real or apparent conflicts of interest. These participants have declared no financial affiliations with any corporate organizations: ■ Daniel Aguilar, MPH ■ Jane F. Beaulieu, MSN ■ Judith Bentkover, PhD ■ Michael A. Bloom, BA ■ Stephen J. Boccuzzi, PhD ■ Bonnie B. Dean, PhD ■ Joaquim Fernandes, BA ■ David Groves, PhD ■ Samuel Joo, MS ■ Hannah Kurth, BA ■ Joshua J. Ofman, MD ■ Dean G. Smith, PhD ■ Brennan M. R. Spiegel, MD, MSHS ■ Judith J. Stephenson, SM ■ Sean Sullivan, JD

These participants are employed by Novartis Pharmaceuticals: ■ Victoria Barghout, MSPH ■ Feride Frech, MPH ■ Kristijan H. Kahler, SM

These participants have disclosed the following relationships with corporate organizations: ■ Brooks Cash, MD, FACP Consultant To: Novartis Pharmaceuticals ■ Ian M. Gralnek, MD, MSHS Research Support From: AstraZeneca Bayer Janssen and Eisai Novartis Pharmaceuticals Roche TAP

Signed disclosures are on file at the offices of The American Journal of Managed Care, Jamesburg, New Jersey.

VOL. 11, NO. 1, SUP.

THE AMERICAN JOURNAL OF MANAGED CARE

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CONTINUING EDUCATION

Economic Impact of Irritable Bowel Syndrome: What Does the Future Hold?

This program is supported by an educational grant from Novartis Pharmaceuticals.

• • • The contents of this supplement may include information regarding the use of products that may be inconsistent with or outside the approved labeling for these products in the United States. Physicians should note that the use of these products outside current approved labeling is considered experimental and are advised to consult prescribing information for these products.

THE AMERICAN JOURNAL OF MANAGED CARE