Embedded Optimization for Input Shaping - Semantic Scholar

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September 2010 Journal Update 1. IEEE Transactions on Control Systems Technology

Embedded Optimization for Input Shaping Van den Broeck, L.; Diehl, M.; Swevers, J.; Dept. of Mech. Eng., K.U. Leuven, Leuven, Belgium This paper appears in: Control Systems Technology, IEEE Transactions on Issue Date: Sept. 2010 Volume: 18 Issue:5 On page(s): 1146 - 1154 ISSN: 1063-6536 INSPEC Accession Number: 11477363 Digital Object Identifier: 10.1109/TCST.2009.2032165 Date of Publication: 09 October 2009 Date of Current Version: 23 August 2010 Sponsored by: IEEE Control Systems Society

Abstract Traditional input shaping filters are linear mappings between reference input and system input. These filters are often unnecessarily conservative with respect to input and output bounds if multiple references with different amplitudes are applied. This conservatism is due to its offline design and linear mapping. This paper presents an online input prefilter design approach to overcome this conservatism. The resulting prefilters are called predictive prefilters because the online design is based on the model predictive control (MPC) framework. By theoretical considerations, simulation results and experimental results, it is shown that this new prefilter is at least as good as traditional prefilters, and can result in substantial gains in settling time. Tests show that a 30% decrease in settling time is possible in a common input shaping application.

2. Biophysical Journal

Real-Time Nanoscopy by Using Blinking Enhanced Quantum Dots Tomonobu M. Watanabe†, ▵, Fujii† and Toshio Yanagida†, ‡

,

, Shingo Fukui‡, ▵, Takashi Jin†, Fumihiko



World Premier International Research Center Initiative, Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan ‡ Soft Biosystem Group, Laboratories for Nanobiology, Graduate School of Frontier Biosciences, Osaka University, Suita, Osaka, Japan ▵

Tomonobu M. Watanabe and Shingo Fukui contributed equally to this work.

Abstract Superresolution optical microscopy (nanoscopy) is of current interest in many biological fields. Superresolution optical fluctuation imaging, which utilizes higher-order cumulant of fluorescence temporal fluctuations, is an excellent method for nanoscopy, as it requires neither complicated optics nor illuminations. However, it does need an impractical number of images for real-time observation. Here, we achieved real-time nanoscopy by modifying superresolution optical fluctuation imaging and enhancing the fluctuation of quantum dots. Our developed quantum dots have higher blinking than commercially available ones. The fluctuation of the blinking improved the resolution when using a variance calculation for each pixel instead of a cumulant calculation. This enabled us to obtain microscopic images with 90-nm and 80-ms spatial-temporal resolution by using a conventional fluorescence microscope without any optics or devices.

Fluorescence Lifetime Imaging Reveals that the Environment of the ATP Binding Site of Myosin in Muscle Senses Force Delisa Ibanez-Garcia†, Jose Requejo-Isidro‡, §, Martin R. Webb¶, Timothy G. West†, Paul French‡ and Michael A. Ferenczi†,

,



Molecular Medicine Section, National Heart and Lung Institute, Imperial College London, London, United Kingdom ‡ Photonics Group, Physics Department, Imperial College London, London, United Kingdom § Unidad de Biofisica, Consejo Superior de Investigaciones Científicas, University of the Basque Country, Leioa, Spain ¶ Medical Research Council, National Institute for Medical Research, London, United Kingdom Corresponding author

Abstract Fluorescence lifetime imaging microscopy is used to demonstrate that different loads applied to a muscle fiber change the microenvironment of the nucleotide binding pocket of myosin. Permeabilized skeletal muscle fibers in rigor were labeled with a fluorescent ATP analog, 3′-DEAC-propylenediamine (pda)-ATP (3′-O-{N-[3-(7diethylaminocoumarin-3-carboxamido)propyl]carbamoyl}ATP), which was hydrolyzed to the diphosphate. Cycles of small-amplitude stretches and releases (