PhD Abstract ID# 400 R. Oftadeh, A. Vaziri, A. Nazarian

Graduate Category: Engineering and Technology Degree Level: PhD Abstract ID# 400

Hierarchical Analysis and Multi-Scale Modeling of Rat Cortical and Trabecular Bone R. Oftadeh, A. Vaziri, A. Nazarian

Ultra-

Scale: 5 mm Ultra-structure Mechanical testing Pycnometry Ashing

Modality Pycnometry Gravimetry Gravimetry Mech Testing Mech Testing

Units g.cm-3 % % N/mm N

Cortical Bone 2.17 (0.017) 66.63 (7.64) 33.37 (7.64) 7199 (270) 737 (110)

Micro-

Methods and Materials

Variable Bone Tissue Density Ash Content Protein Content Stiffness Yield Load Bone Volume Fraction Bone Surface to Volume Ratio Modulus of Elasticity Yield Strength

µCT µCT Mech Testing Mech Testing

mm3/mm3 mm2/mm2 GPa GPa

0.59 (0.03) 3.84 (0.19) 8.50 (2.86) 0.13 (0.02)

0.37 (0.04) 14.44 (2.91) 2.47 (1.68) 0.03 (0.01)