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MANNING & NAPIER FUND, INC. PRO-BLEND ®

Maximum Term Series Class R2: MNHCX | Class S: EXHAX | Class I: MNHIX | Class R: MNHRX

Seeking Alpha / Managing Risk / Truly Active / Flexible Asset Allocation

Risk Management & Flexibility Are Key To Core Equity Investing

Core Equity - A Dual Mandate Seeking alpha is only half the story; managing risk based on the current environment is the other half. We believe a core equity manager needs to focus on both. Further, Truly Active management selects investments that may offer an adequate reward for the risk taken. Growth of $10,000 (04/01/2000 - 09/30/2017)

00

$33,067 24 Months

00 15 Months

37 Months

2015

2014

2013

2012

2011

2010

2009

2008

2007

2006

2005

2004

2003

2002

2001

49 Months

2000

00

$23,651

04/00 08/01 12/02 05/04 09/05 02/07 06/08 10/09 03/11 07/12 12/13 04/15 09/16 Pro-Blend Pro-Blend®Maximum Maximum Term Term Series 1

S&P 500 2

Peak to Peak

Recovery Period

Up/Down Market Capture4

2000 - 2002 Market Drawdown3

(04/01/2000 - 09/30/2017)

MONTHS TO RECOVER 15

97.16% 49

Pro-Blend Maximum Term

1

80.41%

S&P 500

2

2007 - 2009 Market Drawdown3 MONTHS TO RECOVER 24 37 Pro-Blend Maximum Term1

S&P 5002

Up Market

Down Market

Pro-Blend® Maximum Term1 vs S&P 5002

Truly Active Management Active management versus passive management may be the wrong debate, because not all active management is Truly Active. The flexibility that comes with the right kind of active management may add value to your core equity allocation. Passive

Active 83

60

Active share is a useful way to evaluate how different a manager is from an index.

60%

83%

An Active Share score of 60% or higher signifies an active manager.5

Active Share for Pro-Blend® Maximum Term is 83%.6

Flexible Asset Allocation The core equity fund space is dynamic. Many core equity offerings have exposure to a broad array of investment types. We are, however, different from others. We have the flexibility to move to cash, as well as short-term fixed income, to seek to preserve capital depending on the market environment. Equity Range (70% - 95%) 75%

87%

95%

0%

100% LOW* (2Q 2001)

Cash & Fixed Income Range (5% - 30%) 13%

5%

HIGH* (2Q 2009) 3Q 2017

25%

0%

100% LOW* (2Q 2009)

HIGH* (2Q 2001)

3Q 2017

*Representative of Pro-Blend® Maximum Term’s high and low allocation during the time period 04/01/2000 - 09/30/2017.

About Manning & Napier Since 1970, Manning & Napier has delivered solutions that help investors meet their financial goals. We offer a broad range of investment management and benefits products and services to individuals, institutions, and partners. Our truly active, independent, and opportunistic style allows us to manage risk in line with objectives across a variety of market environments.

65

21

77

17

We have a team of approx. 65 research professionals with diverse backgrounds and investment experience

The management team has more than 77 years of combined experience

Pro-Blend® Maximum Term Series has a 21 year track record

We manage approximately $17 billion in equity assets

Data as of 06/30/2017.

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Visit www.manning-napier.com/Advisor or call (888) 825-4493 for additional resources. Annualized Performance (as of 09/30/2017) U.S. Stock Market Since Inception Expense Ratio* Cycle (04/01/2000) (11/01/1995) Pro-Blend® Maximum Term Class S1 13.26% 9.64% 4.98% 7.07% 8.97% 1.09% S&P 5002 18.58% 14.21% 7.44% 5.04% 8.95% N/A 65/20/15 Blended Index7 15.98% 10.97% 6.03% 5.25% 7.99% N/A Performance data quoted represents past performance and does not guarantee future results. The investment return and principal value of an investment will fluctuate so that an investor’s shares, when redeemed, may be worth more or less than their original cost. Current performance may be higher or lower than that quoted. Investors can obtain the most recent month-end performance at www.manning-napier.com or by calling (800) 466-3863. *Includes a shareholder servicing fee of 0.25% for Maximum Term. One Year

Five Year

Ten Year

For more information about any of the Manning & Napier Fund, Inc. Series, you may obtain a prospectus at www.manning-napier.com or by calling (800) 466-3863. Before investing, carefully consider the objectives, risks, charges and expenses of the investment and read the prospectus carefully as it contains this and other information about the investment company. Manning & Napier’s risk mitigation style, which is intended to provide protection in sustained bear markets, may cause underperformance during periods of strong appreciation in the equity markets. Active management may result in more frequent buying and selling of underlying investments, which may have tax implications.

All data is representative of the U.S. Stock Market Cycle 04/01/2000 - 09/30/2017, unless otherwise noted. Statistical measurements shown are calculated using quarterly performance. All periods greater than one year are annualized. Pro-Blend® Maximum Term’s allocation is subject to change. The portfolio has the ability to invest in stocks, both domestic and international, fixed income, including short-term, intermediate-term, and long-term, as well as alternatives and cash. 1 All investments involve risks, including possible loss of principal. Because the fund invests in both stocks and bonds, the value of your investment will fluctuate in response to stock market movements and changes in interest rates. Investing in the fund will also involve a number of other risks, including issuer-specific risk, foreign investment risk, and small-cap/mid-cap risk. Investments in options and futures, like all derivatives, can be highly volatile and involve risks in addition to the risks of the underlying instrument on which the derivative is based, such as counterparty, correlation and liquidity risk. Also, the use of leverage increases exposure to the market and may magnify potential losses. 2 The S&P 500 Total Return Index (S&P 500) is an unmanaged, capitalization-weighted measure of 500 widely held common stocks listed on the New York Stock Exchange, American Stock Exchange, and the Over-the-Counter market. The Index returns assume daily reinvestment of dividends and do not reflect any fees or expenses. Index returns provided by Bloomberg. S&P Dow Jones Indices LLC, a subsidiary of the McGraw Hill Financial, Inc., is the publisher of various index based data products and services and has licensed certain of its products and services for use by Manning & Napier. All such content Copyright © 2017 by S&P Dow Jones Indices LLC and/or its affiliates. All rights reserved. Neither S&P Dow Jones Indices LLC, Dow Jones Trademark Holdings LLC, their affiliates nor their third party licensors make any representation or warranty, express or implied, as to the ability of any index to accurately represent the asset class or market sector that it purports to represent and none of these parties shall have any liability for any errors, omissions, or interruptions of any index or the data included therein. 3 A market drawdown is the peak-to-trough decline during a specific record period of an investment, fund or commodity. A drawdown is usually quoted as the percentage between the peak and the trough. 4 Up market capture ratio is the percent of market return captured by the investment manager’s return relative to the benchmark during positive periods. Down market capture ratio is the percent of market return captured by the investment manager’s return relative to the benchmark during negative periods. 5 Petajisto, Antti. “Active Share and Mutual Fund Performance.” January 15, 2013. Web. 6 Active Share calculation is based on 09/30/2017 holdings data for the Pro-Blend® Maximum Term Series relative to the S&P 500 Total Return Index. Holdings exclude cash, fixed income, and unassigned. Active share can range from 0% to 100%. A high active share indicates that a portfolio’s investments significantly differ from the benchmark, while the investments of a portfolio with a low active share largely mirror the benchmark. 7 The 65/20/15 Blended Index is 65% Russell 3000® Index (Russell 3000), 20% MSCI ACWI ex USA Index (ACWIxUS), and 15% Bloomberg Barclays U.S. Aggregate Bond Index (BAB). Russell 3000 is an unmanaged index that consists of 3,000 of the largest U.S. companies based on total market capitalization. The Index returns are based on a market capitalization-weighted average of relative price changes of the component stocks plus dividends whose reinvestments are compounded daily. Index returns provided by Bloomberg. ACWIxUS is designed to measure large and mid-cap representation across 22 of 23 Developed Markets countries (excluding the U.S.) and 24 Emerging Markets countries. The Index is denominated in U.S. dollars. The Index returns assume daily investment of gross dividends (which do not account for applicable dividend taxation) prior to 12/31/1998, as net returns were not available. Subsequent to 12/31/1998, the Index returns are net of withholding taxes. They assume daily reinvestment of net dividends thus accounting for any applicable dividend taxation. Index returns provided by Bloomberg. BAB is an unmanaged, market value-weighted index of U.S. domestic investment-grade debt issues, including government, corporate, asset-backed, and mortgage-backed securities with maturities of one year or more. Index returns provided by Interactive Data. The returns of the indices do not reflect any fees or expenses. Returns provided are calculated monthly using a blended allocation. Because the fund’s asset allocation will vary over time, the composition of the fund’s portfolio may not match the composition of the comparative Indices. The Manning & Napier Fund, Inc. is managed by Manning & Napier Advisors, LLC. Manning & Napier Investor Services, Inc., an affiliate of Manning & Napier Advisors, LLC, is the distributor of the Fund shares. FUND-IDG-PBMAX001.3 (10/17)