CHANGING TRENDS IN CERVICAL CANCER IN WALES: 1985-2012 Ganiy Opeyemi Abdulrahman Jnr, Academic Clinical Fellow/Specialty Registrar in Obstetrics & Gynaecology, Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne NE1 4LP, United Kingdom.
Introduction Cervical cancer is the commonest malignancy among women below the age of 35years in the United Kingdom.1
Results A total of 5896 women diagnosed with cervical cancer were registered with the Welsh cancer registry between 1985 and 2012.
The highest incidence rate is seen in Merthyr Tydfil, followed by the Isle of Anglesey, Bridgend and Rhondda Cynon Taff while the lowest rates are in Monmouthshire and Newport. Local Authorities
Total
EASR (95% CI)
Anglesey
157
15.1 (11.8-18.4)
Blaenau Gwent
140
12.5 (10.1-15.0)
Bridgend
313
15.0 (12.1-17.9)
Caerphilly
302
11.6 (9.9-13.4)
Cardiff
489
10.5 (9.3-11.7)
Carmarthenshire
374
13.1 (10.3-15.8)
Ceredigion
139
13.1 (9.6-16.5)
Conwy
248
13.5 (11.1-15.8)
Denbighshire
217
14.6 (11.5-17.7)
Flintshire
293
13.6 (10.3-17.0)
Gwynedd
248
13.3 (11.2-15.4)
Merthyr Tydfil
141
15.5 (13.1-17.9)
Monmouthshire
136
10.2 (8.0-12.4)
Risk factors associated with cervical cancer include HPV infection, early age at first sexual intercourse, multiple sexual partners, early age at first full-term pregnancy, multiple births and smoking.
Neath and Port Talbot
308
13.9 (11.3-16.5)
Newport
221
10.2 (8.1-12.3)
Pembrokeshire
266
14.6 (12.2-17.0)
Powys
253
12.9 (9.3-16.5)
There is no study that has addressed the trends of cervical cancer in Wales especially since the introduction of the screening programme in 1988.
Time trends in incidence rates of cervical cancer in Wales, 1985-2012
Rhondda Cynon Taff
546
15.0 (12.4-17.7)
Swansea
440
12.2 (10.0-14.4)
Torfaen
161
11.6 (9.2-14.0)
Vale of Glamorgan
216
11.5 (9.7-13.3)
Aim
There has been a significant decline in the incidence of cervical cancer over the study period with lower rate in 2010-2012 compared to 1985-1987 (RR 0.431 [CI 0.3860.482], p