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CHANGING TRENDS IN CERVICAL CANCER IN WALES: 1985-2012 Ganiy Opeyemi Abdulrahman Jnr, Academic Clinical Fellow/Specialty Registrar in Obstetrics & Gynaecology, Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne NE1 4LP, United Kingdom.

Introduction Cervical cancer is the commonest malignancy among women below the age of 35years in the United Kingdom.1

Results A total of 5896 women diagnosed with cervical cancer were registered with the Welsh cancer registry between 1985 and 2012.

The highest incidence rate is seen in Merthyr Tydfil, followed by the Isle of Anglesey, Bridgend and Rhondda Cynon Taff while the lowest rates are in Monmouthshire and Newport. Local Authorities

Total

EASR (95% CI)

Anglesey

157

15.1 (11.8-18.4)

Blaenau Gwent

140

12.5 (10.1-15.0)

Bridgend

313

15.0 (12.1-17.9)

Caerphilly

302

11.6 (9.9-13.4)

Cardiff

489

10.5 (9.3-11.7)

Carmarthenshire

374

13.1 (10.3-15.8)

Ceredigion

139

13.1 (9.6-16.5)

Conwy

248

13.5 (11.1-15.8)

Denbighshire

217

14.6 (11.5-17.7)

Flintshire

293

13.6 (10.3-17.0)

Gwynedd

248

13.3 (11.2-15.4)

Merthyr Tydfil

141

15.5 (13.1-17.9)

Monmouthshire

136

10.2 (8.0-12.4)

Risk factors associated with cervical cancer include HPV infection, early age at first sexual intercourse, multiple sexual partners, early age at first full-term pregnancy, multiple births and smoking.

Neath and Port Talbot

308

13.9 (11.3-16.5)

Newport

221

10.2 (8.1-12.3)

Pembrokeshire

266

14.6 (12.2-17.0)

Powys

253

12.9 (9.3-16.5)

There is no study that has addressed the trends of cervical cancer in Wales especially since the introduction of the screening programme in 1988.

Time trends in incidence rates of cervical cancer in Wales, 1985-2012

Rhondda Cynon Taff

546

15.0 (12.4-17.7)

Swansea

440

12.2 (10.0-14.4)

Torfaen

161

11.6 (9.2-14.0)

Vale of Glamorgan

216

11.5 (9.7-13.3)

Aim

There has been a significant decline in the incidence of cervical cancer over the study period with lower rate in 2010-2012 compared to 1985-1987 (RR 0.431 [CI 0.3860.482], p